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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T78334 |
Surzebiclimab
BGB-A425 |
||
Surzebiclimab (BGB-A425) 是一种人源化IgG1变体单克隆抗体,专一性地靶向 T 细胞免疫球蛋白和含粘蛋白结构域 3 (TIM-3)。该抗体与人 Tim-3 蛋白的细胞外结构域具有高亲和力(KD=0.36 nM),并因此被广泛应用于癌症研究领域。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPJ-00748 |
Ig kappa Protein, Human, Recombinant (His)
Ig κ chain C region AG,Ig κ,Ig kappa chain C region... |
Human | HEK293 Cells |
Immunoglobulin Kappa is constant region of immunoglobulin light chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humo... |